Recombinant Antigens

HIV1 gp41C

HIV1 gp41C
AGHIV1c
1Product overview
Protein type
 recombinant Ag
Application
 Lateral flow, ELSA, Western blot
2Product specification
HostEscherichia coli
Purity
 > 95%
Molcular weight
30kDa
Form/Buffer
 Liquid/10mM Carbonate buffer, 0.1% sodiumazide(NaN3), pH9.6
Concentration
 > 3.0mg/ml
3Storage & Safety
Storage

* Short term storage : Store at 4℃ 

* Long term storage : Aliquot and store at below -20℃

* Avoid repeated freeze/thaw cycles.

4General information
Note

The strains of HIV-1 can be classified into four groups. The most important group, M(main), is the ‘major’ group and is responsible for the majority of the global HIV epidemic.

The dominant HIV subtype in the Americas, Western Europe and Australasia is subtype B.

As a result, the great majority of HIV clinical research has been conducted in populations where subtype B predominates.


In contrast, there is less research available for subtype C, although just under half of all people living with HIV have subtype C. Subtype C is the dominant form in Southern Africa, Eastern Africa, India, Nepal, and parts of China


Gp41, known as glycoprotein 41, is a subunit of the envelope protein complex of retroviruses which includes human immunodefiiciency (HIV). 


Gp41 is transmembrane protein that contains several sites within its ectodomain that are required for infection of host cells. 


Due to its importance in host cell infection, it has also gained much attention as a potential target for HIV serological test for diagnosis.